Genetic errors linked to life-threatening pregnancy disorder
Scientists have identified genetic errors in women with autoimmune diseases that increase the risk of preeclampsia, a potentially life-threatening condition that occurs in 10 percent of all pregnancies.
View ArticleMouse cancer genome unveils genetic errors in human cancers
Scientists who pioneered sequencing the genomes of cancer patients to find novel genetic changes at the root of the disease now have turned their attention to a laboratory workhorse -- a mouse.
View ArticleDiet-exercise combo best for obese seniors
For obese seniors, dieting and exercise together are more effective at improving physical performance and reducing frailty than either alone.
View ArticleDNA of 50 breast cancer patients decoded
In the single largest cancer genomics investigation reported to date, scientists have sequenced the whole genomes of tumors from 50 breast cancer patients and compared them to the matched DNA of the...
View ArticleCaution for estrogen therapy after hysterectomy
An editorial in the April 6 issue of the Journal of the American Medical Association cautions against estrogen-only hormone therapy in women who have had a hysterectomy because of longstanding evidence...
View ArticleDecoding cancer patients' genomes is powerful diagnostic tool
Two new studies highlight the power of sequencing cancer patients' genomes as a diagnostic tool, helping doctors decide the best course of treatment and researchers identify new cancer susceptibility...
View ArticleProtein keeps sleep-deprived flies ready to learn
(PhysOrg.com) -- A protein that helps the brain develop early in life can fight the mental fuzziness induced by sleep deprivation, according to researchers at Washington University School of Medicine...
View ArticleZebrafish regrow fins using multiple cell types, not identical stem cells
What does it take to regenerate a limb? Biologists have long thought that organ regeneration in animals like zebrafish and salamanders involved stem cells that can generate any tissue in the body. But...
View ArticleEvolution provides clue to blood clotting
A simple cut to the skin unleashes a complex cascade of chemistry to stem the flow of blood. Now, scientists at Washington University School of Medicine in St. Louis have used evolutionary clues to...
View ArticleResearchers block morphine's itchy side effect
Itching is one of the most prevalent side effects of powerful, pain-killing drugs like morphine, oxycodone and other opioids. The opiate-associated itch is so common that even women who get epidurals...
View ArticleUnusual protein helps regulate key cell communication pathway
Charged atoms, or ions, move through tiny pores, or channels, embedded in cell membranes, generating the electrical signals that allow cells to communicate with one another. In new research, scientists...
View ArticleUrinary tract infections steal from hosts' defense arsenals
Humans have known for centuries that copper is a potent weapon against infection. New research shows that the bacteria that cause serious urinary tract infections "know" this, too, and steal copper to...
View ArticleHuman, soil bacteria swap antibiotic-resistance genes: study
Soil bacteria and bacteria that cause human diseases have recently swapped at least seven antibiotic-resistance genes, researchers at Washington University School of Medicine in St. Louis report Aug....
View ArticleFish prone to melanoma get DNA decoded
Scientists at Washington University School of Medicine in St. Louis and elsewhere have decoded the genome of the platyfish, a cousin of the guppy and a popular choice for home aquariums. Among...
View ArticleDiscovery helps show how breast cancer spreads
Researchers at Washington University School of Medicine in St. Louis have discovered why breast cancer patients with dense breasts are more likely than others to develop aggressive tumors that spread....
View ArticlePropofol discovery may aid development of new anesthetics
Researchers at Washington University School of Medicine in St. Louis and Imperial College London have identified the site where the widely used anesthetic drug propofol binds to receptors in the brain...
View ArticleStomach cells naturally revert to stem cells
New research has shown that the stomach naturally produces more stem cells than previously realized, likely for repair of injuries from infections, digestive fluids and the foods we eat.
View ArticleHookworm genome sequenced
Going barefoot in parts of Africa, Asia and South America contributes to hookworm infections, which afflict an estimated 700 million of the world's poor. The parasitic worm lives in the soil and enters...
View ArticleOptical brain scanner goes where other brain scanners can't
Scientists have advanced a brain-scanning technology that tracks what the brain is doing by shining dozens of tiny LED lights on the head. This new generation of neuroimaging compares favorably to...
View ArticleUnintended consequences: More high school math, science linked to more dropouts
As U.S. high schools beef up math and science requirements for graduation, researchers at Washington University in St. Louis have found that more rigorous academics drive some students to drop out.
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